Plasmodium falciparum 3D7 (EPr1)

Plasmodium falciparum 3D7 Assembly and Gene Annotation

About the Plasmodium falciparum genome

Plasmodium falciparum is the malarial parasite most dangerous to humans, accounting for over 90% of all malarial deaths, and was the first species of the genus Plasmodium to be sequenced. It's genome is notable for an exceptionally low GC content of under 20%. In other respects, the genome has a similar size (23.3 Mb) and gene count (about 5300) to other species of malaria.

Assembly

The genome is assembled into 14 chromosomes and is available from the EMBL/Genbank/DDBJ databases under the accession GCA_000002765.1

Annotation

Annotation of the P. falciparum 3D7 genome is provided by GeneDB where the latest sequence data and annotation is constantly updated. Periodic releases are also available from PlasmoDB. PlasmoDB.org hosts genomic and proteomic data (and more) for different species of the parasite eukaryote Plasmodium. It brings together data provided by numerous laboratories worldwide.

Variation

Plasmodium falciparum variation data is a direct import from dbSNP.

References

  1. Genome sequence of the human malaria parasite Plasmodium falciparum.
    Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S et al. 2002. Nature. 419:498-511.
  2. Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.
    Hall N, Pain A, Berriman M, Churcher C, Harris B, Harris D, Mungall K, Bowman S, Atkin R, Baker S et al. 2002. Nature. 419:527-531.
  3. Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum.
    Gardner MJ, Tettelin H, Carucci DJ, Cummings LM, Aravind L, Koonin EV, Shallom S, Mason T, Yu K, Fujii C et al. 1998. Science. 282:1126-1132.
  4. Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum.
    Wilson RJ, Denny PW, Preiser PR, Rangachari K, Roberts K, Roy A, Whyte A, Strath M, Moore DJ, Moore PW et al. 1996. J. Mol. Biol.. 261:155-172.
  5. The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum.
    Bowman S, Lawson D, Basham D, Brown D, Chillingworth T, Churcher CM, Craig A, Davies RM, Devlin K, Feltwell T et al. 1999. Nature. 400:532-538.

More information

General information about this species can be found in Wikipedia.

Statistics

Summary

AssemblyEPr 1, May 2016
Database version94.1
Base Pairs23,292,622
Golden Path Length23,292,622
Genebuild byEnsemblProtists
Genebuild methodGenerated from ENA annotation
Data sourceGeneDB

Gene counts

Coding genes5,362
Non coding genes178
Small non coding genes178
Pseudogenes153
Gene transcripts5,693

Other

Short Variants85,039

About this species