Dictyostelium discoideum Assembly and Gene Annotation

About Dictyostelium discoideum AX4

Dictyostelium discoideum is a species of soil-dwelling amoeba belonging to the phylum Amoebozoa, infraphylum Mycetozoa. Commonly referred to as slime mold, D. discoideum is a eukaryote that transitions from a collection of unicellular amoebae into a multicellular slug and then into a fruiting body within its lifetime. Its unique asexual life cycle consists of four stages: vegetative, aggregation, migration, and culmination. The life cycle of D. discoideum is relatively short, which allows for timely viewing of all stages. The cells involved in the life cycle undergo movement, chemical signaling, and development, which are applicable to human cancer research. The simplicity of its life cycle makes D. discoideum a valuable model organism to study genetic, cellular, and biochemical processes in other organisms.

Picture credit via Wikimedia Commons (Image source)

Taxonomy ID 352472

(Text from Wikipedia.)

More information General information about this species can be found in Wikipedia

Annotation

The data in this site is a direct import from dictyBase, The data used in this release corresponds to the release of dictyBase from 14-Oct-2009 and can be downloaded from here. The latest release from dictyBase can be downloaded from here. Publications using this data should cite the following publication: Fey P, et al. dictyBase - a Dictyostelium bioinformatics resource update. Nucl. Acids Res. 37:D515-19.

References

1. The genome of the social amoeba Dictyostelium discoideum.
   Eichinger L, Pachebat JA, Glckner G, Rajandream MA, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q et al. 2005. Nature. 435:43-57.
2. Novel non-coding RNAs in Dictyostelium discoideum and their expression during development.
   Aspegren A, Hinas A, Larsson P, Larsson A, Sderbom F. 2004. Nucleic Acids Res.. 32:4646-4656.
3. Analyses of cDNAs from growth and slug stages of Dictyostelium discoideum.
   Urushihara H, Morio T, Saito T, Kohara Y, Koriki E, Ochiai H, Maeda M, Williams JG, Takeuchi I, Tanaka Y. 2004. Nucleic Acids Res.. 32:1647-1653.
4. The cDNA sequencing project.
   Urushihara H, Morio T, Tanaka Y. 2006. Methods Mol. Biol.. 346:31-49.

Picture credit: dictyBase. Copyright: M.J. Grimson & R.L. Blanton,
"Biological Sciences Electron Microscopy Laboratory, Texas Tech University.
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Other data

The ESTs sequenced from different stages of Dictyostelium development were also downloaded from dictyBase and aligned to the genome using exonerate.

More information

General information about this species can be found in Wikipedia.