Entamoeba histolytica Assembly and Gene Annotation
About the Entamoeba histolytica genome
Entamoeba histolytica is an anaerobic parasitic protozoan, part of the genus Entamoeba. Predominantly infecting humans and other primates, E. histolytica is estimated to infect about 50 million people worldwide. Entamoeba histolytica (strain HM-1:IMSS), was the first human amoeba to have its genome sequenced, assembled and analyzed. Whole genome shotgun sequencing with small insert libraries was used to carry out sequencing to a 12.5-fold coverage.
The data in this site is a direct import from AmoebaDB, The data used in this release corresponds to the release 1.7 from 11-Jan-2012 and can be downloaded from here. Publications using this data should cite the following publication:
- New assembly, reannotation and analysis of the Entamoeba
histolytica genome reveal new genomic features and protein content
Lorenzi HA, Puiu D, Miller JR, Brinkac LM, Amedeo P, Hall N, Caler EV. 2010. PLoS Negl Trop Dis. 4:e716.
- The genome of the protist parasite Entamoeba
Loftus B, Anderson I, Davies R, Alsmark UC, Samuelson J, Amedeo P, Roncaglia P, Berriman M, Hirt RP, Mann BJ et al. 2005. Nature. 433:865-868.
- EuPathDB: a portal to eukaryotic pathogen
Aurrecoechea C, Brestelli J, Brunk BP, Fischer S, Gajria B, Gao X, Gingle A, Grant G, Harb OS, Heiges M et al. 2010. Nucleic Acids Res.. 38:D415-9.
Picture credit: Dr. George Healy
General information about this species can be found in Wikipedia.