Giardia lamblia Assembly and Gene Annotation

About Giardia lamblia

Giardia lamblia belong to the taxonomica group excavates and it is flagellated protozoan parasite that colonizes and reproduces in the small intestine, causing giardiasis.

Assembly

G. lamblia (ATCC 50803) strain WB, clone C6 genome was sequenced to 11.3 coverage using the whole genome shotgun method. It is 12 Mb in size and contains 6488 predicted open reading frames distributed throughout five chromosomes (chromosome polymorphism has been identified in different strains) and more than 13,100 predicted proteins. Karyotyping studies found chromosome sizes to range from 1.6 to over 3.8 Mb. It is available from the EMBL/Genbank/DDBJ databases under the accession GCA_000002435.1{.constant}

Annotation

The protein coding gene annotation of the Giardia lamblia genome was imported from European Nucleotide Archive (ENA) accession GCA_000002435. G. lamblia genome project are managed by the Marine Biology Laboratories in Woods Hole and involves collaboration from University of Texas at El Paso, University of Arizona at Tucson, and University of Illinois at Urbana-Champaign.

Non-coding RNA genes have been annotated using tRNAScan-SE (Lowe, T.M. and Eddy, S.R. 1997), RFAM (Griffiths-Jones et al 2005), and RNAmmer (Lagesen K.,et al 2007); additional analysis tools have also been applied.

References

1. Genomic minimalism in the early diverging intestinal parasite Giardia lamblia.
   Morrison HG, McArthur AG, Gillin FD, Aley SB, Adam RD, Olsen GJ, Best AA, Cande WZ, Chen F, Cipriano MJ et al. 2007. Science. 317:1921-1926.

Picture credit: Janice Carr

More information

General information about this species can be found in Wikipedia.